PepTalk peptide database

Evidence-graded peptide profiles

One dark, opinionated index. Real evidence signals. No pretending that animal studies, biomarkers, and FDA approvals all mean the same thing.

Strong evidence
3
Moderate evidence
7
Emerging or weak
4
Categories
Evidence tiers
14 profiles

Tirzepatide

Tirzepatide Ā· Dual GIP/GLP-1 agonist Ā· Metabolic / Weight

9.4
/10
StrongMetabolic

The current heavyweight in obesity pharmacology. Bigger outcomes than semaglutide, bigger expectations, and zero room for sloppy titration. Not subtle. Very real.

Cost / mo
$500–1,300
Forms
SubQ
Studies
60+
Read profile
ā˜… Editor's Pick

BPC-157

Body Protection Compound-157 Ā· Pentadecapeptide Ā· Recovery / Gut

9.2
/10
StrongRecovery

The gut-healing peptide that actually has the receipts. Forty-plus studies, oral form that works, and a safety profile we can get behind. Our #1 recovery pick.

Cost / mo
$45–65
Forms
Oral + SubQ
Studies
40+
Read profile

Semaglutide

Semaglutide Ā· GLP-1 receptor agonist Ā· Metabolic / Weight

9.1
/10
StrongMetabolic

The GLP-1 that made peptide medicine mainstream. Real trial data, real weight loss, and very real GI tradeoffs. Legit, not effortless.

Cost / mo
$300–1,200
Forms
Oral + SubQ
Studies
100+
Read profile

TB-500

TB-500 Ā· Thymosin beta-4 fragment Ā· Recovery / Tissue

7.5
/10
ModerateRecovery

The systemic-feeling recovery peptide everyone pairs with BPC-157. Plausible mechanism, thinner evidence, and still not the same thing. Useful, not interchangeable.

Cost / mo
$60–90
Forms
SubQ
Studies
15+
Read profile

Sermorelin

Sermorelin Ā· GHRH analog Ā· Growth Hormone / Conservative use

7.5
/10
ModerateGrowth Hormone

The older-school GHRH peptide with real clinical history and much lower drama than the biohacker favorites. Sensible, milder, and not here to cosplay as HGH. Credible, not flashy.

Cost / mo
$90–150
Forms
SubQ
Studies
15+
Read profile

CJC-1295

CJC-1295 Ā· GHRH analog Ā· Growth Hormone / Recovery

7.0
/10
ModerateGrowth Hormone

The GHRH analog with real pathway signal and wildly inflated physique expectations. Better as a protocol tool than a personality trait. Legit, still not HGH.

Cost / mo
$90–160
Forms
SubQ
Studies
10+
Read profile

Ipamorelin

Ipamorelin Ā· Ghrelin receptor agonist Ā· Growth Hormone / Sleep

7.0
/10
ModerateGrowth Hormone

The tidy GH secretagogue people reach for when older GHRPs feel too messy. Cleaner profile, moderate evidence, and still best used as part of a real protocol. Useful, not magical.

Cost / mo
$80–140
Forms
SubQ
Studies
10+
Read profile

GHK-Cu

GHK-Cu Ā· Copper-binding tripeptide Ā· Recovery / Skin

6.8
/10
ModerateRecovery

The copper peptide with a real wound-healing and skin-quality case, then a lot of extra marketing piled on top. Best when kept local and realistic.

Cost / mo
$40–120
Forms
Topical + SubQ
Studies
20+
Read profile

MK-677

MK-677 (Ibutamoren) Ā· Oral ghrelin agonist Ā· Growth Hormone / Sleep

6.5
/10
ModerateGrowth Hormone

The oral GH-axis compound people love because it skips injections. It also brings appetite, edema, and enough chaos to keep you honest. Convenient, not clean.

Cost / mo
$70–110
Forms
Oral
Studies
20+
Read profile

Selank

Selank Ā· Synthetic heptapeptide Ā· Longevity / Calm

6.3
/10
ModerateLongevity

The calm-and-cognition peptide with enough signal to matter and enough uncertainty to keep the claims on a leash. Interesting, not automatic.

Cost / mo
$70–120
Forms
Intranasal + SubQ
Studies
15+
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NAD+

NAD+ Ā· Cellular coenzyme protocol Ā· Longevity / Energy

5.5
/10
WeakLongevity

The longevity clinic darling with a real biological role and a much fuzzier intervention story. Interesting, expensive, and very easy to oversell. Hype still outpaces proof.

Cost / mo
$200–800
Forms
IV + IM/SubQ
Studies
10+
Read profile

Epitalon

Epitalon Ā· Tetrapeptide Ā· Longevity / Circadian

5.2
/10
WeakLongevity

The longevity peptide that keeps showing up in telomere conversations for a reason, then gets sold far past that reason. Interesting, still unsettled.

Cost / mo
$70–130
Forms
SubQ
Studies
15+
Read profile

DSIP

DSIP Ā· Neuropeptide Ā· Longevity / Sleep

4.8
/10
WeakLongevity

The sleep peptide with a strong name and a much softer evidence base. Worth understanding, not worth pretending is proven. Curious, still thin.

Cost / mo
$50–90
Forms
SubQ
Studies
10 or fewer
Read profile

AOD-9604

AOD-9604 Ā· GH fragment Ā· Metabolic / Fat loss

4.5
/10
WeakMetabolic

The fat-loss peptide with a clean idea and a much less convincing scoreboard. Interesting design, weak payoff, and no reason to confuse it with real obesity medicine. More concept than category leader.

Cost / mo
$90–140
Forms
SubQ
Studies
10+
Read profile